Danshen: Uses, Side Effects, Precautions, Dosing, and Interactions

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Danshenin: A Natural Supplement with Therapeutic Properties


Danshenin, also known as Salvianolic acid B, is a major active compound extracted from the root of the Chinese herb Salvia miltiorrhiza (also known as Danshen or Chinese sage). This supplement has been used in traditional Chinese medicine for centuries to treat various health conditions. Modern research has validated many of the traditional uses of Danshenin, demonstrating its potential for treating cardiovascular diseases, inflammation, liver damage, and more.

Uses of Danshenin

Danshenin has been shown to possess a wide range of therapeutic effects, including:

Cardiovascular Health:

  • Reduces inflammation in blood vessels
  • Improves blood circulation
  • Lowers blood pressure
  • Protects against heart attacks and strokes

Anti-inflammatory Properties:

  • Suppresses inflammatory responses
  • Reduces pain and swelling
  • May benefit conditions such as arthritis, inflammatory bowel disease, and asthma

Liver Protection:

  • Protects liver cells from damage
  • Reduces inflammation and fibrosis in the liver
  • May benefit conditions such as hepatitis and liver cirrhosis

Neuroprotective Effects:

  • Reduces oxidative stress in the brain
  • Protects against neuronal damage
  • May improve cognitive function

Antioxidant Properties:

  • Scavenges free radicals
  • Protects cells from oxidative damage
  • May contribute to overall health and well-being

Side Effects of Danshenin

Danshenin is generally considered safe when taken in recommended doses. However, as with any supplement, there is a potential for side effects, which may include:

  • Mild gastrointestinal symptoms (nausea, vomiting, diarrhea)
  • Increased menstrual bleeding
  • Skin rashes or itching
  • Dizziness or headache


Before taking Danshenin, it is important to consider the following precautions:

  • Pregnant or breastfeeding women should not take Danshenin.
  • Individuals with bleeding disorders or taking blood thinners should use Danshenin with caution.
  • Danshenin may interact with certain medications, such as warfarin and cyclosporine.
  • If you have any underlying health conditions, consult with your healthcare provider before taking Danshenin.


The recommended dosage of Danshenin varies depending on the specific health condition being treated. It is important to follow the dosage instructions provided by your healthcare provider or on the product label.

Typical Dosage Ranges:

  • Cardiovascular health: 100-300 mg per day
  • Anti-inflammatory: 50-200 mg per day
  • Liver protection: 100-200 mg per day
  • Neuroprotection: 50-150 mg per day


Danshenin is typically taken orally in capsule or tablet form. It can be taken with or without food.


Danshenin may interact with the following medications:

  • Warfarin: Danshenin may increase the risk of bleeding when taken with warfarin.
  • Cyclosporine: Danshenin may increase the levels of cyclosporine in the blood, leading to increased side effects.
  • Antiplatelet medications: Danshenin may increase the risk of bleeding when taken with antiplatelet medications, such as aspirin or clopidogrel.


Danshenin is a natural supplement with a wide range of therapeutic properties. It has been traditionally used in Chinese medicine and has gained scientific support for its effects on cardiovascular health, inflammation, liver damage, and neuroprotection. While Danshenin is generally safe when taken in recommended doses, it is important to be aware of potential side effects and interactions with medications. Before taking Danshenin, consult with your healthcare provider to determine if it is appropriate for you.

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