Borage: Uses, Side Effects, Precautions, and Dosing

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Boragein: A Natural Supplement with Potential Health Benefits


Boragein is a natural supplement derived from the seeds of the borage plant (Borago officinalis). It is a rich source of gamma-linolenic acid (GLA), an essential fatty acid that cannot be produced by the body and must be obtained from dietary sources. GLA has been shown to play a role in various physiological processes, including inflammation, skin health, and immune function.

Uses of Boragein

Boragein has been used traditionally for centuries to treat a variety of ailments. Modern research has supported some of these traditional uses and identified additional potential health benefits. Here are some of the most common uses of boragein:

  • Eczema and other skin conditions: GLA, the primary active ingredient in boragein, has been shown to improve symptoms of eczema, psoriasis, and other skin conditions. It reduces inflammation and helps to restore the integrity of the skin barrier.
  • Rheumatoid arthritis: Boragein may help to alleviate pain and stiffness associated with rheumatoid arthritis. GLA has anti-inflammatory properties that can reduce swelling and joint pain.
  • PMS and menstrual cramps: GLA may help to reduce menstrual pain, cramps, and other PMS symptoms. It has anti-prostaglandin effects, which can help to control inflammation and uterine contractions.
  • Autoimmune diseases: Boragein has been studied for its potential role in managing autoimmune diseases, such as multiple sclerosis and lupus. GLA may help to suppress inflammation and regulate the immune system.
  • Heart health: GLA has been shown to have beneficial effects on heart health, including lowering blood pressure and improving cholesterol levels. It may also help to reduce the risk of heart disease.
  • Cognitive function: Some studies have suggested that boragein may improve cognitive function and reduce the risk of age-related cognitive decline. GLA has neuroprotective properties that may help to protect against damage to the brain.

Side Effects of Boragein

Boragein is generally well-tolerated, but some side effects can occur. The most common side effects include:

  • Gastrointestinal upset, such as nausea, vomiting, or diarrhea
  • Skin rashes
  • Headaches
  • Fatigue

Rare but more serious side effects can include:

  • Liver damage
  • Seizures
  • Bleeding problems


Before taking boragein, it is important to consult with a healthcare professional, especially if you have any underlying medical conditions or are taking any medications. Boragein may interact with certain medications, such as blood thinners and anticonvulsants.

Boragein should not be taken by people with:

  • Liver disease
  • A history of seizures
  • A bleeding disorder
  • Pregnancy or breastfeeding


The optimal dosage of boragein varies depending on the purpose for which it is being used. It is recommended to start with a low dose and gradually increase it as tolerated. The usual dosage range is 500 to 1500 mg per day, taken in divided doses.


Boragein is a natural supplement that may offer a range of health benefits, including reducing inflammation, improving skin health, and alleviating menstrual cramps. It is important to consult with a healthcare professional before taking boragein to determine if it is right for you and to establish an appropriate dosage.

Additional Information

  • GLA can also be obtained from other dietary sources, such as black currant seed oil, evening primrose oil, and spirulina.
  • Boragein supplements are typically standardized to contain a specific amount of GLA.
  • It is important to store boragein supplements properly in a cool, dark place to prevent degradation.

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