Yohimbe: Uses, Side Effects, Precautions, and Dosing

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Yohimbine: A Comprehensive Guide to Uses, Side Effects, Precautions, and Dosing


Yohimbine is an alkaloid extracted from the bark of the Pausinystalia yohimba tree, native to West Africa. It has been traditionally used as an aphrodisiac and to treat erectile dysfunction. In recent years, yohimbine has gained popularity as a supplement for fat loss and athletic performance.

Uses of Yohimbine

1. Erectile Dysfunction

Yohimbine is a potent alpha-2 receptor antagonist, which means it blocks the action of alpha-2 receptors in the body. This can lead to increased blood flow to the penis, which can help improve erectile function. Yohimbine is effective in treating both organic and psychogenic erectile dysfunction.

2. Fat Loss

Yohimbine has been shown to promote fat loss by increasing the activity of the sympathetic nervous system. This can lead to increased lipolysis (fat breakdown) and decreased lipogenesis (fat synthesis). Yohimbine may be particularly effective at reducing stubborn belly fat.

3. Athletic Performance

Yohimbine may improve athletic performance by increasing energy levels, reducing fatigue, and enhancing focus. It may also increase the release of growth hormone, which can promote muscle growth and recovery.

Side Effects of Yohimbine

Yohimbine can cause a variety of side effects, including:

  • Anxiety
  • Insomnia
  • Headache
  • Nausea
  • Vomiting
  • Diarrhea
  • Tremors
  • Increased heart rate and blood pressure

Serious side effects are rare but can include:

  • Seizures
  • Heart attack
  • Stroke


Yohimbine should not be used by individuals with:

  • Severe heart disease
  • High blood pressure
  • Kidney disease
  • Liver disease
  • Bipolar disorder
  • Schizophrenia

Yohimbine should also be used with caution in individuals taking antidepressants or other medications that affect the nervous system.


The recommended dosage of yohimbine for most purposes is 5 to 10 mg per day. This dosage should be divided into two or three doses throughout the day. Yohimbine is best taken on an empty stomach.

It is important to note that yohimbine can interact with many medications, so it is important to talk to your doctor before taking it.


Yohimbine is a powerful supplement with a variety of potential benefits. However, it is important to be aware of the potential side effects and precautions before taking it. If you are considering taking yohimbine, talk to your doctor first to make sure it is right for you.

Additional Information

Legal Status

Yohimbine is legal in the United States and most other countries. However, it is banned by the International Olympic Committee and other sports organizations.


An overdose of yohimbine can be fatal. Symptoms of an overdose include:

  • Confusion
  • Seizures
  • Hallucinations
  • Coma

If you suspect an overdose of yohimbine, seek medical attention immediately.


Yohimbine withdrawal can occur after prolonged use. Symptoms of withdrawal include:

  • Anxiety
  • Insomnia
  • Depression
  • Fatigue

Yohimbine withdrawal is typically mild and will resolve within a few days. However, if you experience severe withdrawal symptoms, talk to your doctor.

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